Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736042 | 0.84 | GCK (0.51) | GCK | |
| SCHEMBL17486282 | 0.82 | HTR2C (0.47) | CYP11B1CYP11B2IDO1CYP19A1NPC1 | |
| SCHEMBL23877246 | 0.76 | L3MBTL1 (0.50) | SIGMAR1EBPTMEM97NPC1RAB9A | |
| SCHEMBL14586643 | 0.72 | MAPT (0.61) | NPC1RAB9A | |
| SCHEMBL10153422 | 0.70 | SIGMAR1 (0.45) | CYP11B1CYP11B2SIGMAR1EBPTMEM97 | |
| SCHEMBL17912813 | 0.70 | CYP11B1 (0.56) | CYP11B1CYP11B2IDO1NPC1RAB9A | |
| SCHEMBL13339111 | 0.70 | MAPT (0.48) | SIGMAR1EBPTMEM97 | |
| SCHEMBL20805427 | 0.70 | HTR2C (0.48) | CYP11B1CYP11B2IDO1SIGMAR1EBP | |
| SCHEMBL19612224 | 0.70 | MAPT (0.66) | CYP11B1CYP11B2IDO1NPC1RAB9A | |
| SCHEMBL12301146 | 0.70 | SCN4A (0.53) | CYP11B1CYP11B2IDO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174890-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |