Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20809994 | 0.89 | ALDH1A1 (0.57) | ALDH1A1KDM4ETDP1MAPK1KMT2A | |
| SCHEMBL20810155 | 0.86 | KMT2A (0.54) | ALDH1A1KDM4ETDP1MAPK1KMT2A | |
| SCHEMBL20810034 | 0.81 | TSHR (0.55) | ALDH1A1KMT2ALMNAMAPTPOLB | |
| SCHEMBL20810014 | 0.81 | KMT2A (0.62) | ALDH1A1TDP1MAPK1KMT2ALMNA | |
| SCHEMBL20810151 | 0.81 | TDP1 (0.53) | ALDH1A1KDM4ETDP1MAPK1KMT2A | |
| SCHEMBL20810037 | 0.80 | TDP1 (0.59) | ALDH1A1KDM4ETDP1MAPK1KMT2A | |
| SCHEMBL20810066 | 0.80 | NPC1 (0.40) | ALDH1A1TDP1MAPTPOLBL3MBTL1 | |
| SCHEMBL20810165 | 0.79 | TDP1 (0.51) | ALDH1A1KDM4ETDP1MAPK1KMT2A | |
| SCHEMBL20810052 | 0.79 | L3MBTL1 (0.45) | ALDH1A1KDM4ETDP1KMT2AMAPT | |
| SCHEMBL20810150 | 0.78 | TDP1 (0.50) | ALDH1A1KDM4ETDP1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190077777-A1 | NICOTINIC ACID DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF | XIAMEN INSTITUTE OF RARE EARTH MATERIALS (CN) | 2019-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077777-A1 | NICOTINIC ACID DERIVATIVES, THEIR PREPARATION AND THE USE THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCAR3, NAPRT | ALDH1A1 1755/4885KDM4E 4802/4885TDP1 4152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.