SCHEMBL20812911

SCHEMBL20812911

c1ccc(-c2ccc(N(c3ccc(-c4cccc(-c5ccccc5)c4)cc3)c3cccc(-c4ccc(-n5c6ccccc6c6cc7ccccc7cc65)cc4)c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TSPO P30536 4/20 0.35
HDAC4 P56524 1/20 0.35
NPY5R Q15761 1/20 0.31
PTPN1 P18031 1/20 0.31
FGFR1 P11362 1/20 0.31
DYRK3 O43781 1/20 0.31
CLK1 P49759 1/20 0.31
CLK2 P49760 1/20 0.31
CLK3 P49761 1/20 0.31
GSK3B P49841 1/20 0.31
CDK5 Q00535 1/20 0.31
DYRK1A Q13627 1/20 0.31
CDK5R1 Q15078 1/20 0.31
DYRK2 Q92630 1/20 0.31
CLK4 Q9HAZ1 1/20 0.31
DYRK1B Q9Y463 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20813038 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24948467 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24948460 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24946758 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24946746 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24947286 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24948463 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24374023 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL24947285 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4
SCHEMBL15138153 0.99 L3MBTL1 (0.41) KDM4EATML3MBTL1TSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10464895-B2 Compound, material for organic electroluminescence elements, organic electroluminescence element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-11-05 US disclosed
US-20190077754-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD (JP) 2019-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10464895-B2 Compound, material for organic electroluminescence elements, organic electroluminescence element, and electronic device PIEZO1, RER1, L1CAM KDM4E 2962/4885ATM 2301/4885L3MBTL1 266/4885
US-20190077754-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENTS, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE PIEZO1, RER1, L1CAM KDM4E 2962/4885ATM 2301/4885L3MBTL1 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.