SCHEMBL20814852

SCHEMBL20814852

CC1=C(C)C([Zr](C2C=C(c3cccc(Cl)c3)c3ccccc32)=[Si](C)C)C(C)=C1C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.32
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20814887 0.91 PTPRC (0.32)
SCHEMBL20814726 0.88
SCHEMBL20815057 0.87 BRD4 (0.30) BRD4
SCHEMBL20814796 0.86 HTR1A (0.30) HTR1AHTR7
SCHEMBL20814873 0.86 HSD11B1 (0.32)
SCHEMBL20814968 0.85 KIF11 (0.32)
SCHEMBL20814848 0.85
SCHEMBL20815080 0.84
SCHEMBL20814894 0.84
SCHEMBL20814831 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935297-B1 BRIDGED METALLOCENE COMPOUNDS, CATALYST SYSTEMS AND PROCESSES FOR POLYMERIZATION THEREWITH EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-03-20 EP claimed