Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.39 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.39 |
| ▸ | RPS17 | P08708 | 1/20 | 0.39 |
| ▸ | RPSA | P08865 | 1/20 | 0.39 |
| ▸ | RPS2 | P15880 | 1/20 | 0.39 |
| ▸ | RPL35A | P18077 | 1/20 | 0.39 |
| ▸ | RPL7 | P18124 | 1/20 | 0.39 |
| ▸ | RPL17 | P18621 | 1/20 | 0.39 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.39 |
| ▸ | RPS3 | P23396 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17927290 | 0.82 | ACP3 (0.48) | ALDH1A1LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL28353118 | 0.81 | MEN1 (0.52) | ALDH1A1LMNATSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL14270314 | 0.81 | MEN1 (0.52) | ALDH1A1LMNATSHRCYP3A4SMN1; SMN2 | |
| SCHEMBL16788837 | 0.76 | LMNA (0.47) | ALDH1A1LMNATSHRCYP2C19MAPT | |
| SCHEMBL14022413 | 0.76 | LMNA (0.47) | ALDH1A1LMNATSHRCYP2C19MAPT | |
| SCHEMBL14270275 | 0.76 | LMNA (0.47) | ALDH1A1LMNATSHRCYP2C19MAPT | |
| SCHEMBL19435775 | 0.76 | PDE2A (0.51) | ALDH1A1TSHRCYP3A4KDM4EMAPT | |
| SCHEMBL15418479 | 0.75 | LMNA (0.34) | LMNATSHRCYP3A4SMN1; SMN2CYP2C19 | |
| SCHEMBL14270127 | 0.75 | CES1 (0.45) | ALDH1A1LMNATSHRKDM4EMAPT | |
| SCHEMBL15382013 | 0.74 | NOS3 (0.41) | LMNACYP2C19ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681504-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | Icagen, Inc. (US) | 2020-07-22 | — | — | EP | disclosed |
| WO-2019055754-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN, INC. (US) | 2019-03-21 | — | — | WO | disclosed |