Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29787140 | 1.00 | S1PR1 (0.33) | S1PR1EGLN1DDR1LRRK2 | |
| SCHEMBL17504810 | 0.90 | DDR1 (0.36) | EGLN1DDR1 | |
| SCHEMBL29787145 | 0.85 | USP1 (0.33) | S1PR1EGLN1 | |
| SCHEMBL20819268 | 0.85 | USP1 (0.33) | S1PR1EGLN1 | |
| SCHEMBL25669933 | 0.84 | S1PR1 (0.31) | S1PR1 | |
| SCHEMBL21761834 | 0.83 | EGLN1 (0.32) | EGLN1DDR1 | |
| SCHEMBL17504809 | 0.83 | DDR1 (0.34) | EGLN1DDR1 | |
| SCHEMBL29787144 | 0.83 | DDR1 (0.34) | EGLN1DDR1 | |
| SCHEMBL20829885 | 0.83 | LRRK2 (0.32) | EGLN1LRRK2 | |
| SCHEMBL21750107 | 0.80 | EGLN1 (0.42) | EGLN1DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684768-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| EP-3684768-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| US-11413291-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-08-16 | — | — | US | disclosed |
| US-20200268760-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-20200268760-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3684768-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019053182-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-21 | — | — | WO | disclosed |
| WO-2019053182-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11413291-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, ACHE, SQOR | S1PR1 2950/4885EGLN1 3167/4885DDR1 4459/4885 |
| US-20200268760-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | S1PR1 2950/4885EGLN1 3167/4885DDR1 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.