Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342839 | 1.00 | CYP2C9 (0.47) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL20826420 | 0.84 | ACHE (0.36) | CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL22319459 | 0.83 | CYP2C9 (0.43) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL22342337 | 0.77 | HSD11B1 (0.39) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL22342844 | 0.77 | TSHR (0.38) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL22342841 | 0.72 | ALDH1A1 (0.46) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL12846189 | 0.72 | ALDH1A1 (0.46) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL22342843 | 0.71 | ALDH1A1 (0.44) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL22319458 | 0.71 | ALDH1A1 (0.44) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A | |
| SCHEMBL20560402 | 0.70 | ALDH1A1 (0.61) | CYP2C9CYP2C19ALDH1A1CYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161863-B2 | Chiral catalyst and method for asymmetric reduction of an imine | DALHOUSIE UNIVERSITY (CA) | 2021-11-02 | — | — | US | disclosed |
| US-20200255463-A1 | CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE | DALHOUSIE UNIVERSITY (CA) | 2020-08-13 | — | — | US | disclosed |
| WO-2019051585-A1 | CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE | DALHOUSIE UNIVERSITY (CA) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255463-A1 | CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE | C1R, C5, C1S | CYP2C9 43/4885CYP2C19 65/4885ALDH1A1 381/4885 |
| US-11161863-B2 | Chiral catalyst and method for asymmetric reduction of an imine | C1R, C5, C1S | CYP2C9 43/4885CYP2C19 65/4885ALDH1A1 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.