Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.51 |
| ▸ | PGK1 | P00558 | 1/20 | 0.48 |
| ▸ | PGK2 | P07205 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16081109 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HIF1AADORA2AADORA2BADORA3 | |
| SCHEMBL16081012 | 0.87 | HIF1A (0.76) | ALDH1A1HIF1AADORA2AADORA2BADORA3 | |
| SCHEMBL20820220 | 0.87 | HIF1A (0.76) | ALDH1A1HIF1AADORA2AADORA2BADORA3 | |
| SCHEMBL2218888 | 0.85 | ADORA2A (0.70) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL20820173 | 0.85 | P2RY1 (0.55) | ALDH1A1 | |
| SCHEMBL16081121 | 0.85 | P2RY1 (0.55) | ALDH1A1 | |
| SCHEMBL19186882 | 0.84 | ADORA2A (0.59) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL13468488 | 0.84 | ADORA2A (0.59) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL16081039 | 0.84 | ADORA2A (0.59) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL8970907 | 0.83 | ADORA2A (0.62) | HIF1AADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2019-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10231986-B2 | Amino acid phosphoramidate pronucleotides of 2′-cyano, azido and amino nucleosides for the treatment of HCV | PNP, RNGTT, NSUN2 | ALDH1A1 2726/4885HIF1A 3443/4885ADORA2A 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.