Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | YAP1 | P46937 | 1/20 | 0.53 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.53 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ufenamate SCHEMBL29376700 | 0.83 | CYP1A2 (0.72) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| Ufenamate SCHEMBL36095 | 0.83 | CYP1A2 (0.72) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL12715082 | 0.82 | LMNA (0.91) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL11579676 | 0.80 | LMNA (0.67) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL11809785 | 0.80 | LMNA (0.56) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| Hydrochloric Acid SCHEMBL11816840 | 0.79 | LMNA (0.55) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL10597386 | 0.79 | LMNA (0.71) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| Etofenamate SCHEMBL25152 | 0.79 | LMNA (1.00) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| SCHEMBL3812938 | 0.79 | LMNA (0.70) | LMNACYP1A2CYP2C9CYP2C19RXFP1 | |
| Colfenamate SCHEMBL2110641 | 0.77 | LMNA (0.68) | LMNACYP1A2CYP2C9CYP2C19RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10233198-B2 | Pro-drugs of NSAIAs with very high skin and membranes penetration rates and their new medicinal uses | TECHFIELDS PHARMA CO., LTD. (CN) | 2019-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233198-B2 | Pro-drugs of NSAIAs with very high skin and membranes penetration rates and their new medicinal uses | MYLK2, ALPI, SLC2A2 | LMNA 13/4885CYP1A2 3524/4885CYP2C9 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.