SCHEMBL20823280

SCHEMBL20823280

CCC(CC)/C(C)=N/OCc1ccccc1/C(=C\OC)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
HIF1A Q16665 7/20 0.36
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18292027 0.90 HIF1A (0.38) ALDH1A1HIF1A
SCHEMBL22875945 0.87 HIF1A (0.34) ALDH1A1HIF1A
SCHEMBL18292032 0.85 HIF1A (0.39) ALDH1A1HIF1A
SCHEMBL9743087 0.84 PTGS2 (0.39) ALDH1A1HIF1A
SCHEMBL20822604 0.83 HIF1A (0.38) ALDH1A1HIF1A
SCHEMBL18291973 0.83 HIF1A (0.42) HIF1A
SCHEMBL20823276 0.81 CYP1A2 (0.37) ALDH1A1HIF1ATSHR
SCHEMBL18291974 0.81 HIF1A (0.39) HIF1A
SCHEMBL7741989 0.79 HIF1A (0.38) HIF1A
SCHEMBL9076609 0.78 CES2 (0.38) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 US disclosed
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 ALDH1A1 902/4885HIF1A 3683/4885TSHR 4878/4885
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 ALDH1A1 902/4885HIF1A 3683/4885TSHR 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.