SCHEMBL18291973

SCHEMBL18291973

CO/C=C(/C(=O)OC)c1ccccc1CO/N=C(C)/C(C)=N/OC

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.42
PTGS2 P35354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743087 0.92 PTGS2 (0.39) HIF1APTGS2
SCHEMBL18291974 0.90 HIF1A (0.39) HIF1APTGS2
SCHEMBL828228 0.89 HIF1A (0.47) HIF1APTGS2
SCHEMBL7740759 0.89 HIF1A (0.39) HIF1APTGS2
SCHEMBL828229 0.89 HIF1A (0.47) HIF1APTGS2
SCHEMBL7741989 0.88 HIF1A (0.38) HIF1APTGS2
SCHEMBL18292032 0.88 HIF1A (0.39) HIF1APTGS2
SCHEMBL20823276 0.88 CYP1A2 (0.37) HIF1APTGS2
SCHEMBL20822604 0.86 HIF1A (0.38) HIF1A
SCHEMBL18292027 0.86 HIF1A (0.38) HIF1APTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289271-A2 METHOD AND POLYMERIC MATERIAL HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST MOSQUITOES SYNGENTA PARTICIPATIONS AG (CH) 2023-12-13 EP disclosed
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 US disclosed
US-20210007353-A1 COMPOUNDS AND COMPOSITIONS HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST INSECT PESTS SYNGENTA PARTICIPATIONS AG (CH) 2021-01-14 US disclosed
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 US disclosed
WO-2016193267-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2016-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 HIF1A 3683/4885PTGS2 2877/4885
US-20210007353-A1 COMPOUNDS AND COMPOSITIONS HAVING KNOCK-DOWN OR BLOOD FEED INHIBITION ACTIVITY AGAINST INSECT PESTS NIT2, KISS1R, NNMT HIF1A 4126/4885PTGS2 2231/4885
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 HIF1A 3683/4885PTGS2 2877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.