SCHEMBL20823554

SCHEMBL20823554

CO/C=C(/C(=O)OC)c1ccccc1COc1nccnc1C#N

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.35
HCRTR2 O43614 1/20 0.35
PLCG1 P19174 1/20 0.35
HIF1A Q16665 4/20 0.35
SGMS2 Q8NHU3 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
FFAR1 O14842 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5688372 0.81 SGMS2 (0.40) SGMS2KDM4E
SCHEMBL29709962 0.81 SGMS2 (0.40) SGMS2KDM4E
SCHEMBL18292000 0.81 HIF1A (0.38) HIF1ASGMS2
SCHEMBL30368058 0.81 HIF1A (0.38) HIF1ASGMS2
SCHEMBL20822846 0.81 MAPK8 (0.47) SGMS2KDM4EALDH1A1
SCHEMBL29470271 0.81 HPGD (0.43) KDM4EALDH1A1
SCHEMBL30367824 0.78 SGMS2 (0.42) HIF1ASGMS2
SCHEMBL18291950 0.78 SGMS2 (0.42) HIF1ASGMS2
SCHEMBL7171950 0.78 MAPK1 (0.41) HIF1AKDM4EALDH1A1
SCHEMBL7171946 0.78 MAPK1 (0.41) HIF1AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2023-04-20 US disclosed
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME SYNGENTA PARTICIPATIONS AG (CH) 2019-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123440-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 HCRTR1 1430/4885HCRTR2 2112/4885PLCG1 267/4885
US-20190082687-A1 MOSQUITO VECTOR CONTROL COMPOSITIONS, METHODS AND PRODUCTS UTILIZING SAME DDT, MLEC, MSMO1 HCRTR1 1430/4885HCRTR2 2112/4885PLCG1 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.