Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171946 | 1.00 | MAPK1 (0.41) | MAPK1KMT2AHIF1AKDM4EALDH1A1 | |
| SCHEMBL8171322 | 0.90 | MAPK1 (0.42) | MAPK1KMT2AHIF1AKDM4EALDH1A1 | |
| SCHEMBL8724335 | 0.89 | MAPK1 (0.39) | MAPK1KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL26935194 | 0.87 | POLB (0.41) | KMT2AHIF1AKDM4EHSD17B10 | |
| SCHEMBL9256030 | 0.85 | GABRA5 (0.39) | KMT2AHIF1AKDM4E | |
| SCHEMBL12671601 | 0.85 | GABRA5 (0.39) | KMT2AHIF1AKDM4E | |
| SCHEMBL203004 | 0.84 | SMN1; SMN2 (0.39) | MAPK1HIF1AKDM4E | |
| SCHEMBL7786334 | 0.84 | HIF1A (0.39) | KMT2AHIF1AKDM4E | |
| SCHEMBL31289594 | 0.84 | SMN1; SMN2 (0.39) | MAPK1HIF1AKDM4E | |
| SCHEMBL29358985 | 0.84 | SMN1; SMN2 (0.39) | MAPK1HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653258-B1 | Pyridinyl-substituted- methyl 3-methoxy-2-phenylacrylate derivatives; agricultural miticides and nematocides | SYNGENTA LIMITED (GB) | 2003-11-25 | — | — | US | disclosed |
| US-6020524-A | Process for the preparation of 2-(pyrid-2-yloxymethyl)phenylacetates as pesticide intermediates | ZENECA LIMITED (GB) | 2000-02-01 | — | — | US | disclosed |
| EP-0854866-B1 | PROCESS FOR THE PREPARATION OF 2-(PYRID-2-YLOXYMETHYL)PHENYLACETATES AS PESTICIDE INTERMEDIATES | ZENECA LTD (GB) | 1999-11-17 | — | — | EP | disclosed |
| US-5942623-A | REACTING A SPECIFIC PYRIDINE HAVING A LEAVING GROUP IN THE 2 POSITION WITH A DI-ALKALI METAL SALT OF 2-HYDROXYMETHYLPHENYLACETIC ACID; USED TO MAKE METHYL 2-(2-(PYRID-2-YLOXYMETHYL)PHENYL)-3-METHOXYACRYLATE PESTICIDES | ZENECA LIMITED (GB) | 1999-08-24 | — | — | US | disclosed |
| EP-0854866-A1 | PROCESS FOR THE PREPARATION OF 2-(PYRID-2-YLOXYMETHYL)PHENYLACETATES AS PESTICIDE INTERMEDIATES | ZENECA LIMITED (GB) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997012864-A1 | PROCESS FOR THE PREPARATION OF 2-(PYRID-2-YLOXYMETHYL)PHENYLACETATES AS PESTICIDE INTERMEDIATES | ZENECA LIMITED (GB) | 1997-04-10 | — | — | WO | disclosed |
| US-5438059-A | Derivatives of propenoic acid; stereoisomers; applying to plants | ZENECA LIMITED (GB) | 1995-08-01 | — | — | US | disclosed |
| EP-0363818-B1 | Oximether derivatives, process for their preparation and fungicides containing them | BASF AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5021581-A | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-04 | — | — | US | disclosed |
| EP-0278595-A2 | Fungicides | ZENECA LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |