SCHEMBL2082409

SCHEMBL2082409

BrCCCCCCCCN(CCCCCCCCBr)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.38
EGFR P00533 1/20 0.37
ERBB2 P04626 1/20 0.37
TSHR P16473 1/20 0.36
KCNH2 Q12809 2/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
ADRA2A P08913 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 1/20 0.34
JAK2 O60674 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2079764 1.00 SIGMAR1 (0.38) SIGMAR1EGFRERBB2TSHRKCNH2
SCHEMBL2082458 1.00 SIGMAR1 (0.38) SIGMAR1EGFRERBB2TSHRKCNH2
SCHEMBL11181087 0.83 KCNH2 (0.42) SIGMAR1KCNH2
SCHEMBL11056830 0.81 TSHR (0.41) EGFRERBB2TSHRKCNH2CHRM2
SCHEMBL23504507 0.81 SIGMAR1 (0.46) SIGMAR1EGFRERBB2TSHR
SCHEMBL17841727 0.80 KCNH2 (0.43) SIGMAR1KCNH2CHRM2HTR1AADRA2A
SCHEMBL11779466 0.79 TSHR (0.52) SIGMAR1TSHRKCNH2CHRM2HTR1A
SCHEMBL25276956 0.78 NPC1 (0.53) SIGMAR1TSHRKCNH2NPC1JAK2
SCHEMBL25224466 0.78 NPC1 (0.53) SIGMAR1TSHRKCNH2NPC1JAK2
SCHEMBL25224593 0.78 NPC1 (0.53) SIGMAR1TSHRKCNH2NPC1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897735-B2 Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2011-03-01 US disclosed
US-20100090210-A1 COMPOUND HAVING THIOL ANCHORING GROUP, METHOD OF SYNTHESIZING THE SAME, AND MOLECULAR ELECTRONIC DEVICE HAVING MOLECULAR ACTIVE LAYER FORMED USING THE COMPOUND LEE HYOYOUNG 2010-04-15 US disclosed
US-20090294762-A1 COMPOUND HAVING THIOL ANCHORING GROUP, METHOD OF SYNTHESIZING THE SAME, AND MOLECULAR ELECTRONIC DEVICE HAVING MOLECULAR ACTIVE LAYER FORMED USING THE COMPOUND LEE HYOYOUNG 2009-12-03 US disclosed
US-7538199-B2 Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2009-05-26 US disclosed
US-20070073058-A1 Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE 2007-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070073058-A1 Compound having thiol anchoring group, method of synthesizing the same, and molecular electronic device having molecular active layer formed using the compound TST, ICMT, DNTT SIGMAR1 4500/4885EGFR 2749/4885ERBB2 1912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.