Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PBK | Q96KB5 | 2/20 | 0.39 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5555738 | 1.00 | EPHX1 (0.46) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR | |
| SCHEMBL1469604 | 1.00 | EPHX1 (0.46) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR | |
| SCHEMBL475548 | 0.94 | SLC6A1 (0.50) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR | |
| SCHEMBL1968950 | 0.94 | SLC6A1 (0.50) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR | |
| SCHEMBL148965 | 0.94 | SLC6A1 (0.50) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR | |
| Hydrochloric Acid SCHEMBL17560394 | 0.92 | SLC6A1 (0.48) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR | |
| SCHEMBL184265 | 0.85 | — | — | |
| SCHEMBL1749149 | 0.85 | — | — | |
| SCHEMBL512691 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL23778361 | 0.83 | EPHX1 (0.50) | EPHX1SMN1; SMN2SLC6A1SLC6A11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302418-A | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-113840820-B | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2024-05-03 | — | — | CN | disclosed |
| CN-116102533-A | Aromatic heterocyclic compound and application thereof | 中国科学院上海药物研究所 | 2023-05-12 | — | — | CN | disclosed |
| CN-110194770-B | Peptidyl arginine deiminase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| US-11254676-B2 | Pyrazole derivative compound and use thereof | HANMI PHARM. CO., LTD. (KR) | 2022-02-22 | — | — | US | disclosed |
| CN-113840820-A | Phthalazinone compounds and uses thereof | ST制药株式会社 | 2021-12-24 | — | — | CN | disclosed |
| EP-3907225-A1 | IMIDAZOPYRIDINE DERIVATIVE COMPOUNDS AND USE OF SAME | Hanmi Pharm. Co., Ltd. (KR) | 2021-11-10 | — | — | EP | disclosed |
| CN-113365996-A | Imidazopyridine derivative compounds and uses thereof | 韩美药品株式会社 | 2021-09-07 | — | — | CN | disclosed |
| US-20210009591-A1 | PYRAZOLE DERIVATIVE COMPOUND AND USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2021-01-14 | — | — | US | disclosed |
| EP-3760628-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-20200407370-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | NANJING TRANSTHERA BIOSCIENCES CO., LTD. (CN) | 2020-12-31 | — | — | US | disclosed |
| WO-2020242245-A1 | PHTHALAZINONE COMPOUNDS AND USE THEREOF | 에스티팜 주식회사 | 2020-12-03 | — | — | WO | disclosed |
| WO-2020159285-A1 | IMIDAZOPYRIDINE DERIVATIVE COMPOUNDS AND USE OF SAME | 한미약품 주식회사 | 2020-08-06 | — | — | WO | disclosed |
| EP-3681877-A1 | PYRAZOLE DERIVATIVE COMPOUND AND USE THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2020-07-22 | — | — | EP | disclosed |
| CN-111094265-A | Pyrazole derivative compound and use thereof | 韩美药品株式会社 | 2020-05-01 | — | — | CN | disclosed |
| WO-2019161803-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-08-29 | — | — | WO | disclosed |
| WO-2019054766-A1 | PYRAZOLE DERIVATIVE COMPOUND AND USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2019-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009591-A1 | PYRAZOLE DERIVATIVE COMPOUND AND USE THEREOF | KDM1A, KDM3A, KDM1B | EPHX1 2528/4885SMN1; SMN2 1145/4885SLC6A1 1585/4885 |
| US-20200407370-A1 | PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF | PADI4, PADI2, PADI1 | EPHX1 2840/4885SMN1; SMN2 3915/4885SLC6A1 4010/4885 |
| US-11254676-B2 | Pyrazole derivative compound and use thereof | KDM1A, KDM3A, KDM1B | EPHX1 2528/4885SMN1; SMN2 1145/4885SLC6A1 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.