Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23432350 | 0.86 | EGFR (0.40) | EGFRAPPMEN1APAF1NPC1 | |
| SCHEMBL19070076 | 0.77 | EGFR (0.37) | EGFRAPPMEN1APAF1NPC1 | |
| SCHEMBL23428954 | 0.76 | EGFR (0.36) | EGFRAPPMEN1APAF1NPC1 | |
| SCHEMBL21120789 | 0.75 | TP53 (0.38) | MAPT | |
| SCHEMBL21020940 | 0.75 | EGFR (0.34) | EGFRAPPMAPT | |
| SCHEMBL11132613 | 0.75 | EGFR (0.38) | EGFRAPPMEN1APAF1NPC1 | |
| SCHEMBL18508987 | 0.74 | ALOX5 (0.35) | MAPT | |
| SCHEMBL22242785 | 0.73 | ESR2 (0.42) | MEN1KMT2AMAPT | |
| SCHEMBL21021658 | 0.73 | ALDH1A1 (0.43) | EGFRAPP | |
| SCHEMBL18896546 | 0.73 | HMGCR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |