Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24495630 | 0.71 | NPSR1 (0.38) | NPSR1KMT2AHDAC1HDAC6NOTUM | |
| SCHEMBL13369575 | 0.71 | NPSR1 (0.38) | NPSR1KMT2AHDAC1HDAC6NOTUM | |
| SCHEMBL13594207 | 0.70 | NPSR1 (0.37) | NPSR1KMT2AHDAC1HDAC6MTNR1A | |
| SCHEMBL13465562 | 0.67 | NPSR1 (0.40) | NPSR1KMT2AHDAC1HDAC6MTNR1A | |
| SCHEMBL8136808 | 0.65 | DRD2 (0.43) | HDAC6MTNR1A | |
| SCHEMBL12045440 | 0.62 | MTNR1A (0.38) | NPSR1KMT2AHDAC1HDAC6MTNR1A | |
| SCHEMBL13089099 | 0.61 | AURKA (0.41) | NPSR1KMT2AHDAC1HDAC6NOTUM | |
| SCHEMBL11210850 | 0.60 | KMT2A (0.57) | NPSR1KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL12133623 | 0.60 | KMT2A (0.76) | NPSR1KMT2AHDAC1HDAC6ALDH1A1 | |
| SCHEMBL7625144 | 0.59 | KMT2A (0.42) | NPSR1KMT2AHDAC1HDAC6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |