Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 9/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26939102 | 0.88 | KIF11 (0.45) | KIF11ESR1ESR2ARHSD11B1 | |
| SCHEMBL10268650 | 0.86 | KIF11 (0.46) | KIF11ESR1ESR2S1PR1DAO | |
| SCHEMBL20811702 | 0.86 | DAO (0.40) | KIF11ESR1ESR2ARHSD11B1 | |
| SCHEMBL29335336 | 0.83 | KIF11 (0.47) | KIF11ESR1ESR2AR | |
| SCHEMBL21101914 | 0.80 | RXRA (0.36) | KIF11ESR1ESR2KLF10 | |
| SCHEMBL18899605 | 0.80 | ESR1 (0.46) | KIF11ESR1ESR2ARKLF10 | |
| SCHEMBL15746150 | 0.79 | KIF11 (0.42) | KIF11ESR1ESR2ARHSD11B1 | |
| SCHEMBL23592890 | 0.78 | ALDH1A1 (0.40) | KIF11ESR1ESR2ARHSD11B1 | |
| SCHEMBL10304793 | 0.76 | KIF11 (0.48) | KIF11 | |
| SCHEMBL20717777 | 0.74 | ESR1 (0.62) | KIF11ESR1ESR2ARKLF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055590-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. (US) | 2019-03-21 | — | — | WO | disclosed |