Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30524707 | 0.89 | VNN1 (0.46) | CA2 | |
| SCHEMBL20811392 | 0.78 | LOX (0.52) | — | |
| SCHEMBL13804351 | 0.74 | GAA (0.53) | — | |
| SCHEMBL20811416 | 0.74 | F2 (0.35) | — | |
| SCHEMBL25794740 | 0.74 | CA2 (0.53) | CA2ALDH1A1 | |
| SCHEMBL13804371 | 0.72 | ALDH1A1 (0.53) | CA2ALDH1A1 | |
| SCHEMBL20826067 | 0.72 | HPGD (0.55) | — | |
| SCHEMBL15743825 | 0.72 | GRM5 (0.42) | ALDH1A1 | |
| SCHEMBL30524782 | 0.71 | VNN1 (0.49) | CA2ALDH1A1 | |
| SCHEMBL568566 | 0.71 | MEN1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055590-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. (US) | 2019-03-21 | — | — | WO | disclosed |