SCHEMBL20827

SCHEMBL20827

[O]CC(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2474279 0.82
SCHEMBL28523131 0.77
SCHEMBL143314 0.77 THRB (0.35)
SCHEMBL1535878 0.75
SCHEMBL185946 0.74 THRB (0.39)
SCHEMBL9778150 0.72 THRB (0.43)
SCHEMBL187513 0.72 THRB (0.43)
SCHEMBL21633726 0.72 THRB (0.43)
SCHEMBL21633789 0.72 THRB (0.43)
SCHEMBL28346028 0.72 THRB (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2594 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117043140-A Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances 拜耳公司 2023-11-10 CN claimed
US-20230159560-A1 METHODS OF USING HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS APTUIT (VERONA) SRL, AN EVOTEC COMPANY (IT) 2023-05-25 US claimed
US-11652238-B2 Electrolyte solution for non-aqueous electrolytic solution battery and non-aqueous electrolyte solution battery using same CENTRAL GLASS CO., LTD. (JP) 2023-05-16 US claimed
US-11528907-B2 Heteroaryl-triazole and heteroaryl-tetrazole compounds as pesticides BAYER AKTIENGESELLSCHAFT (DE) 2022-12-20 US claimed
US-20220362161-A1 COLOR-CODED AND SIZED LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OFPREPARING AND USING THE SAME VARIAN MEDICAL SYSTEMS, INC. 2022-11-17 US claimed
EP-4065579-A1 HETEROCYCLIC COMPOUNDS AS DELTA-5 DESATURASE INHIBITORS AND METHODS OF USE Amgen Inc. (US) 2022-10-05 EP claimed
US-11426355-B2 Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same VARIAN MEDICAL SYSTEMS, INC. (US) 2022-08-30 US claimed
CN-114728167-A Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use 安进公司 2022-07-08 CN claimed
CN-108701864-B Electrolyte for nonaqueous electrolyte battery and nonaqueous electrolyte battery using same 中央硝子株式会社 2022-05-24 CN claimed
EP-3993120-A1 NONAQUEOUS ELECTROLYTE AND NONAQEUOUS ELECTROLYTE SECONDARY BATTERY Central Glass Co., Ltd. (JP) 2022-05-04 EP claimed
EP-0254588-B1 Imidazo[4,5-b] pyridine compounds, process for preparing same and pharmaceutical compositions containing same TOKYO TANABE COMPANY LIMITED (JP) 1992-01-15 EP claimed
US-5026717-A Glutamate inhibitors RHONE-POULENC SANTE (FR) 1991-06-25 US claimed
US-4980356-A ANTICONVULSANTS; ANTISPASMODIC AGENTS; MUSCULAR AND NERVOUS SYSTEMS DISORDERS RHONE-POULENC SANTE (FR) 1990-12-25 US claimed
US-4966937-A AND PROCESSING AIDS AND CURING ETHYL CORPORATION (US) 1990-10-30 US claimed
US-4935437-A (Substituted aralkyl) heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-19 US claimed
EP-0250198-B1 BIS-AZOLYL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-02-28 EP claimed
US-4866086-A PHENYLTRIAZOLYL OLEFINIC AROMATASE INHIBITORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-09-12 US claimed
EP-0299683-A2 Heterocyclic olefinic compounds and their use as aromatase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-01-18 EP claimed
EP-0296749-A1 (Substituted aralkyl) heterocyclic compounds ZENECA LIMITED (GB) 1988-12-28 EP claimed
EP-0250198-A2 Bis-azolyl compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-23 EP claimed