SCHEMBL185946

SCHEMBL185946

[O]CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
LMNA P02545 1/20 0.33
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7567002 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL28881034 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL187513 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL28342728 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL28881707 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL9778150 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL28346028 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL21633789 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL21633726 0.97 THRB (0.43) THRBLMNACA2
SCHEMBL28342696 0.97 THRB (0.43) THRBLMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140050978-A1 ADDITIVE FOR POSITIVE ELECTRODES OF LITHIUM SECONDARY BATTERIES, AND POSITIVE ELECTRODE FOR LITHIUM SECONDARY BATTERIES PLEXTRONICS, INC. (US) 2014-02-20 US claimed
EP-2665116-A1 ADDITIVE FOR POSITIVE ELECTRODES OF LITHIUM SECONDARY BATTERIES, AND POSITIVE ELECTRODE FOR LITHIUM SECONDARY BATTERIES Plextronics, Inc. (US) 2013-11-20 EP claimed
US-8268959-B2 Suitable for binding high explosives, and may also be used as explosives in their own right; materials possess high energy density and are highly amenable to chemical modification thereby allowing for modification to the physical properties of the material; tacky and rubbery nature THE SECRETARY OF STATE FOR DEFENSE (GB) 2012-09-18 US claimed
EP-1960456-A1 NOVEL ENERGETIC POLYPHOSPHAZENES THE SECRETARY OF STATE FOR DEFENCE (GB) 2008-08-27 EP claimed
WO-2006032882-A1 NOVEL ENERGETIC POLYPHOSPHAZENES THE SECRETARY OF STATE FOR DEFENCE (GB) 2006-03-30 WO claimed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
WO-2024101172-A1 (HETERO)ARYL UREA COMPOUND AND INSECTICIDE 日本曹達株式会社 2024-05-16 WO disclosed
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
EP-4365180-A1 RARE EARTH COMPLEX Tosoh Corporation (JP) 2024-05-08 EP disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-2402351-B1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO (JP) 2013-10-09 EP disclosed
US-8268959-B2 Suitable for binding high explosives, and may also be used as explosives in their own right; materials possess high energy density and are highly amenable to chemical modification thereby allowing for modification to the physical properties of the material; tacky and rubbery nature THE SECRETARY OF STATE FOR DEFENSE (GB) 2012-09-18 US disclosed
US-20120053356-A1 NOVEL ENERGETIC POLYPHOSPHAZENES THE SECRETARY OF STATE FOR DEFENSE (GB) 2012-03-01 US disclosed
US-20120037890-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME MITSUI CHEMICALS, INC. 2012-02-16 US disclosed
EP-2402351-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-01-04 EP disclosed
EP-1960456-A1 NOVEL ENERGETIC POLYPHOSPHAZENES THE SECRETARY OF STATE FOR DEFENCE (GB) 2008-08-27 EP disclosed
US-20080108784-A1 Suitable for binding high explosives, and may also be used as explosives in their own right; materials possess high energy density and are highly amenable to chemical modification thereby allowing for modification to the physical properties of the material; tacky and rubbery nature DEFENSE, THE SECRETARY OF THE STATE FOR (GB) 2008-05-08 US disclosed
WO-2006032882-A1 NOVEL ENERGETIC POLYPHOSPHAZENES THE SECRETARY OF STATE FOR DEFENCE (GB) 2006-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120037890-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME LEF1, ZRANB2, AFF1 THRB 1023/4885LMNA 2250/4885CA2 1264/4885
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent L3MBTL3, L3MBTL1, L3MBTL4 THRB 2027/4885LMNA 4405/4885CA2 1131/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 THRB 3672/4885LMNA 1829/4885CA2 2422/4885
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RPS10, H1-10, OR10J3 THRB 3672/4885LMNA 1829/4885CA2 2422/4885
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 THRB 1472/4885LMNA 4131/4885CA2 275/4885
US-20120053356-A1 NOVEL ENERGETIC POLYPHOSPHAZENES ACLY, PEBP1, DDX42 THRB 4184/4885LMNA 3123/4885CA2 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.