SCHEMBL187513

SCHEMBL187513

[O]CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
LMNA P02545 1/20 0.38
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28342696 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL7567002 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL28342728 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL28881034 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL28346028 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL28881707 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL9778150 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL21633726 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL21633789 1.00 THRB (0.43) THRBLMNACA2CA1MMP1
SCHEMBL185946 0.97 THRB (0.39) THRBLMNACA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-05-28 US disclosed
EP-4371979-A1 FORMAMIDE DERIVATIVE AND AGRICULTURAL OR HORTICULTURAL PLANT DISEASE CONTROL AGENT Kumiai Chemical Industry Co., Ltd. (JP) 2024-05-22 EP disclosed
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-04-23 US disclosed
EP-3808738-B1 PYRAZOLE DERIVATIVE AND HARMFUL ORGANISM-CONTROLLING AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2024-04-17 EP disclosed
US-11944009-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-03-26 US disclosed
EP-3974433-B1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO (JP) 2024-02-21 EP disclosed
EP-4317160-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Kumiai Chemical Industry Co., Ltd. (JP) 2024-02-07 EP disclosed
CN-117186663-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学工业株式会社 2023-12-08 CN disclosed
EP-3162799-A1 FLUOROALKYLATING AGENT Ihara Chemical Industry Co., Ltd. (JP) 2017-05-03 EP disclosed
US-20160190469-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-30 US disclosed
US-8778510-B2 Pyrromethene-boron complex compounds and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2014-07-15 US disclosed
EP-2402351-B1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO (JP) 2013-10-09 EP disclosed
US-20120037890-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME MITSUI CHEMICALS, INC. 2012-02-16 US disclosed
EP-2402351-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTRO- LUMINESCENT ELEMENTS USING SAME Idemitsu Kosan Co., Ltd. (JP) 2012-01-04 EP disclosed
EP-0536200-B1 FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS MINNESOTA MINING & MFG (US) 1995-10-11 EP disclosed
EP-0536200-A1 FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS. MINNESOTA MINING & MFG (US) 1993-04-14 EP disclosed
US-5087672-A Lower birefringence and viscosity, increased hydrophobicity MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-02-11 US disclosed
WO-1991019773-A1 FLUORINE-CONTAINING ACRYLATE AND METHACRYLATE SIDE-CHAIN LIQUID CRYSTAL MONOMERS AND POLYMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120037890-A1 PYRROMETHENE-BORON COMPLEX COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME LEF1, ZRANB2, AFF1 THRB 1023/4885LMNA 2250/4885CA2 1264/4885
US-11944009-B2 Compound, material for organic electroluminescent element, organic electroluminescent element, and electronic device LEF1, RER1, OR10J3 THRB 2551/4885LMNA 2751/4885CA2 2496/4885
US-11964957-B2 Pyrazole derivative and harmful organism-controlling agent L3MBTL3, L3MBTL1, L3MBTL4 THRB 2027/4885LMNA 4405/4885CA2 1131/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 THRB 3672/4885LMNA 1829/4885CA2 2422/4885
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RPS10, H1-10, OR10J3 THRB 3672/4885LMNA 1829/4885CA2 2422/4885
US-11993578-B2 Pyrazole-3-carboxylic acid amide derivative and pest control agent H1-3, HDAC3, H1-0 THRB 1472/4885LMNA 4131/4885CA2 275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.