SCHEMBL208276

SCHEMBL208276

[CH2]COC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL28839559 0.89 CHRNB2 (0.48)
SCHEMBL1415938 0.75
Ethylene SCHEMBL21679941 0.73 TSHR (0.52)
Formaldehyde SCHEMBL4454552 0.73 TSHR (0.52)
SCHEMBL767783 0.72
SCHEMBL2547540 0.72 LMNA (0.57)
SCHEMBL1415947 0.71
SCHEMBL1891223 0.69
SCHEMBL9864363 0.69
SCHEMBL7771111 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103118626-B Dental mill blank KURARAY NORITAKE DENTAL INC. (JP) 2015-08-05 CN claimed
CN-102083403-B Dental composition and composite resin KURARAY MEDICAL INC 2013-10-09 CN claimed
US-20130210769-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2013-08-15 US claimed
US-8431607-B2 Compounds and compositions as inhibitors of cannabinoid receptor 1 activity IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) 2013-04-30 US claimed
US-RE42353-E1 Quinazoline derivatives and pharmaceutical compositions containing them ASTRAZENECA UK LIMITED (GB) 2011-05-10 US claimed
US-20110071144-A1 QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ZENECA LIMITED (GB) 2011-03-24 US claimed
US-20100234365-A1 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2010-09-16 US claimed
EP-2121598-A2 COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY IRM LLC (BM) 2009-11-25 EP claimed
CN-101589075-A Multi-part redox-curing-type composition KURARAY MEDICAL INC (JP) 2009-11-25 CN claimed
US-20080312273-A1 Quinoline Derivatives Having Vegf Inhibiting Activity HENNEQUIN LAURENT FRANCOIS ANDRE 2008-12-18 US claimed
EP-0307804-A2 Cephem compound and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-03-22 EP claimed
EP-0131374-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES PFIZER INC. (US) 1988-11-23 EP claimed
EP-0280771-A1 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-09-07 EP claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-0121502-B1 NOVEL PENEM COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THEIR PREPARATION SCHERING CORPORATION (US) 1987-04-08 EP claimed
US-4619783-A BACTERICIDES PFIZER INC. (US) 1986-10-28 US claimed
EP-0131374-A1 Process and intermediates for the preparation of penem derivatives PFIZER INC. (US) 1985-01-16 EP claimed
EP-0121502-A1 Novel penem compounds, pharmaceutical compositions containing them, processes for their preparation SCHERING CORPORATION (US) 1984-10-10 EP claimed
EP-0000636-A1 Penem compounds, processes for their preparation, their use in pharmaceutical compositions and azetidinones used in their preparation GLAXO GROUP LIMITED (GB) 1979-02-07 EP claimed
US-4078146-A TREATMENT OF CARDIO-VASCULAR DISORDERS AKTIEBOLAGET HASSLE (SW) 1978-03-07 US claimed