Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20828642 | 0.82 | — | — | |
| SCHEMBL20828969 | 0.77 | ESR1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL11415517 | 0.68 | CYP3A4 (0.35) | CYP3A4TSHR | |
| SCHEMBL170558 | 0.67 | CYP1A2 (0.33) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL9508130 | 0.65 | ILK (0.35) | GAAALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL22010830 | 0.65 | NUAK1 (0.33) | ALDH1A1POLBCYP3A4TSHR | |
| SCHEMBL13475178 | 0.64 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL16365298 | 0.63 | — | — | |
| SCHEMBL30876 | 0.62 | HDAC3 (0.35) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL12433600 | 0.62 | ALDH1A1 (0.49) | GAAALDH1A1MEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019052973-A1 | DIBENZOFURAN AND DIBENZOTHIOPHENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-03-21 | — | — | WO | disclosed |