Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14380259 | 0.81 | MAOA (0.65) | MAOAMAOBCYP19A1LIMK1CYP11B2 | |
| SCHEMBL20829599 | 0.81 | GPR3 (0.44) | MAOACYP19A1NPC1MAPTRAB9A | |
| SCHEMBL28512593 | 0.81 | MAOA (0.65) | MAOAMAOBCYP19A1LIMK1CYP11B2 | |
| SCHEMBL19764657 | 0.81 | MAOA (0.65) | MAOAMAOBCYP19A1LIMK1CYP11B2 | |
| SCHEMBL7930812 | 0.78 | GPR3 (0.46) | CYP19A1GPR3HTR2A | |
| SCHEMBL22413744 | 0.77 | MAOA (0.43) | MAOAMAOBCYP19A1LIMK1CYP11B2 | |
| SCHEMBL20829703 | 0.73 | ATM (0.36) | CYP19A1CDC25BMAPK10 | |
| SCHEMBL12854062 | 0.71 | RPS6KA3 (0.56) | MAOAMAOBRPS6KA3TNFMAPT | |
| SCHEMBL12854064 | 0.71 | RPS6KA3 (0.56) | MAOAMAOBRPS6KA3TNFMAPT | |
| SCHEMBL3066734 | 0.71 | MAOA (0.87) | MAOAMAOBLIMK1CDC25BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686201-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019052565-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF | 广东东阳光药业有限公司 | 2019-03-21 | — | — | WO | disclosed |