Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099596 | 0.95 | CA2 (0.47) | CA2CA9PAOXSLC6A5MEN1 | |
| SCHEMBL15057676 | 0.93 | PAOX (0.47) | CA2CA9PAOXSLC6A5MEN1 | |
| SCHEMBL28901062 | 0.89 | CA2 (0.50) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL13887521 | 0.86 | CA2 (0.48) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL16014560 | 0.85 | CA2 (0.47) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL28480824 | 0.83 | CA2 (0.46) | CA2CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL13655619 | 0.81 | CA2 (0.44) | CA2CA9MEN1KMT2A | |
| SCHEMBL31491499 | 0.81 | SLC6A5 (0.43) | CA2PAOXSLC6A5CA1 | |
| SCHEMBL23353390 | 0.80 | CASP2 (0.52) | CA2CA9MEN1KMT2A | |
| SCHEMBL16345817 | 0.80 | CA2 (0.43) | CA2CA9MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111920959-B | ROS (reactive oxygen species) -responsive heparin polysaccharide nano prodrug compound based on click reaction, nano preparation, and preparation method and application thereof | 中国药科大学 | 2022-03-25 | — | — | CN | claimed |
| CN-111920959-A | ROS (reactive oxygen species) -responsive heparin polysaccharide nano prodrug compound based on click reaction, nano preparation, and preparation method and application thereof | 中国药科大学 | 2020-11-13 | — | — | CN | claimed |
| CN-111920959-B | ROS (reactive oxygen species) -responsive heparin polysaccharide nano prodrug compound based on click reaction, nano preparation, and preparation method and application thereof | 中国药科大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-111920959-A | ROS (reactive oxygen species) -responsive heparin polysaccharide nano prodrug compound based on click reaction, nano preparation, and preparation method and application thereof | 中国药科大学 | 2020-11-13 | — | — | CN | disclosed |
| EP-3240573-B1 | ENZYMATIC CONJUGATION OF POLYPEPTIDES | INNATE PHARMA (FR) | 2019-03-20 | — | — | EP | disclosed |