Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | UGCG | Q16739 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20830396 | 0.88 | ALDH1A1 (0.56) | RAB9AMEN1KMT2AALDH1A1UGCG | |
| SCHEMBL20830481 | 0.81 | ALDH1A1 (0.49) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL13400250 | 0.80 | RAB9A (0.60) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL20735081 | 0.75 | RAB9A (0.56) | RAB9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11990862 | 0.74 | ALDH1A1 (0.70) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL12341700 | 0.74 | ESR1 (0.63) | RAB9AMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL16965593 | 0.72 | NPSR1 (0.48) | MEN1KMT2AALDH1A1TSHRL3MBTL1 | |
| SCHEMBL20735076 | 0.71 | RAB9A (0.52) | RAB9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL20735114 | 0.71 | RAB9A (0.52) | RAB9AMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL13400255 | 0.70 | MEN1 (0.71) | RAB9AMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900239-B1 | DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, OCULAR DISEASES AND RELATED DISORDERS | WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC (US) | 2019-03-20 | — | — | EP | disclosed |