Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | UGCG | Q16739 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20830463 | 0.88 | RAB9A (0.56) | ALDH1A1POLBKMT2AMEN1UGCG | |
| SCHEMBL16965593 | 0.81 | NPSR1 (0.48) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL20830460 | 0.79 | ESR1 (0.49) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL29832586 | 0.79 | ESR1 (0.49) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL17948241 | 0.76 | PRMT1 (0.68) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL20735130 | 0.76 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL20735229 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL11747305 | 0.73 | ALDH1A1 (0.62) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL20735081 | 0.73 | RAB9A (0.56) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL7491321 | 0.72 | POLB (0.63) | ALDH1A1POLBKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900239-B1 | DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, OCULAR DISEASES AND RELATED DISORDERS | WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC (US) | 2019-03-20 | — | — | EP | disclosed |