Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381628 | 0.80 | TMEM97 (0.67) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL1091362 | 0.78 | TMEM97 (0.64) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL1804995 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL29690338 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL13218890 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL13939142 | 0.76 | GFER (0.59) | CA2SLC6A2ALDH1A1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL8576229 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL274906 | 0.76 | TMEM97 (1.00) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL15701213 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ESR1ESR2KDM4E | |
| SCHEMBL7528215 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2341915-B1 | PHOSPHORYLATED DENDRIMERS AS ANTIINFLAMMATORY DRUGS | CENTRE NAT RECH SCIENT (FR) | 2019-03-20 | — | — | EP | disclosed |