Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11530047 | 0.90 | KDM4E (0.70) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL7381628 | 0.80 | TMEM97 (0.67) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL1091362 | 0.78 | TMEM97 (0.64) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL8576229 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL2549390 | 0.76 | TAAR1 (0.61) | ALDH1A1HTR1AADRA2ASLC6A2CYP2C19 | |
| SCHEMBL24153432 | 0.76 | ALDH1A1 (0.60) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL15701213 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL20831067 | 0.76 | TMEM97 (0.61) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL17922518 | 0.76 | TAAR1 (0.61) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A | |
| SCHEMBL274906 | 0.76 | TMEM97 (1.00) | TMEM97SIGMAR1ALDH1A1HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067069-B1 | HYDROGELS BASED ON POLYMERS OF DEXTRAN TYRAMINE AND TYRAMINE CONJUGATES OF NATURAL POLYMERS | HY2CARE B V (NL) | 2023-07-26 | — | — | EP | disclosed |
| EP-3067069-A1 | HYDROGELS BASED ON POLYMERS OF DEXTRAN TYRAMINE AND TYRAMINE CONJUGATES OF NATURAL POLYMERS | University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) (NL) | 2016-09-14 | — | — | EP | disclosed |
| EP-2498824-B1 | HYDROGELS BASED ON POLYMERS OF DEXTRAN TYRAMINE AND TYRAMINE CONJUGATES OF NATURAL POLYMERS | UNIV TWENTE INST FOR BIOMEDICAL TECHNOLOGY AND TECHNICAL MEDICINE MIRA (NL) | 2016-04-20 | — | — | EP | disclosed |
| US-9132201-B2 | Hydrogels based on polymers of dextran tyramine and tyramine conjugates of natural polymers | UNIVERSITY OF TWENTE, INSTITUTE FOR BIOMEDICAL AND TECHNICAL MEDICINE (MIRA) (NL) | 2015-09-15 | — | — | US | disclosed |
| US-20150250890-A1 | METHOD FOR PREPARING IN SITU-FORMED HYDROGEL USING ENZYME-IMMOBILIZED SUPPORT, AND BIOMEDICAL USE THEREOF | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2015-09-10 | — | — | US | disclosed |
| US-20120276069-A1 | HYDROGELS BASED ON POLYMERS OF DEXTRAN TYRAMINE AND TYRAMINE CONJUGATES OF NATURAL POLYMERS | HY2CARE B.V. (NL) | 2012-11-01 | — | — | US | disclosed |
| EP-2498824-A2 | HYDROGELS BASED ON POLYMERS OF DEXTRAN TYRAMINE AND TYRAMINE CONJUGATES OF NATURAL POLYMERS | University of Twente, Institute for Biomedical Technology and Technical Medicine (MIRA) (NL) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011059326-A2 | HYDROGELS BASED ON POLYMERS OF DEXTRAN TYRAMINE AND TYRAMINE CONJUGATES OF NATURAL POLYMERS | UNIVERSITY OF TWENTE, INSTITUTE FOR BIOMEDICAL TECHNOLOGY AND TECHNICAL MEDICINE (MIRA) (NL) | 2011-05-19 | — | — | WO | disclosed |
| US-3987053-A | ANTIMICROBIAL | GRUPPO LEPETIT S.P.A. (IT) | 1976-10-19 | — | — | US | disclosed |
| US-3954789-A | 2-Nitroimidazole derivatives | GRUPPO LEPETIT S.P.A. (IT) | 1976-05-04 | — | — | US | disclosed |