Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.57 |
| ▸ | HTR2B | P41595 | 15/20 | 0.57 |
| ▸ | HTR1A | P08908 | 14/20 | 0.57 |
| ▸ | HTR6 | P50406 | 12/20 | 0.57 |
| ▸ | HTR3A | P46098 | 11/20 | 0.57 |
| ▸ | HTR1D | P28221 | 8/20 | 0.54 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR1B | P28222 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 2/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818249 | 0.82 | TRPC5 (0.55) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL20817850 | 0.75 | TRPC5 (0.58) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL14081025 | 0.75 | POLB (0.76) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL25695016 | 0.75 | HTR7 (0.54) | HTR7HTR2BHTR1AHTR6HTR3A | |
| Hydrochloric Acid SCHEMBL20818166 | 0.74 | POLB (0.73) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL5758664 | 0.68 | NCF1 (0.45) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL25616990 | 0.68 | POLB (0.65) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL3803829 | 0.67 | HTR7 (0.59) | HTR7HTR2BHTR1AHTR6HTR3A | |
| Hydrochloric Acid SCHEMBL4810850 | 0.67 | NCF1 (0.44) | HTR7HTR2BHTR1AHTR6HTR3A | |
| SCHEMBL9240435 | 0.66 | HTR7 (0.40) | HTR7HTR2BHTR1AHTR6HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |