Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | DRD4 | P21917 | 2/20 | 0.62 |
| ▸ | DRD3 | P35462 | 2/20 | 0.62 |
| ▸ | TRPC5 | Q9UL62 | 10/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831869 | 0.89 | ALDH1A1 (0.66) | ALDH1A1DRD2DRD4DRD3TRPC5 | |
| SCHEMBL20831874 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TRPC5POLBTIPARPKCNH2 | |
| SCHEMBL20831875 | 0.86 | ALDH1A1 (0.65) | ALDH1A1TRPC5POLBTIPARPKCNH2 | |
| SCHEMBL20831880 | 0.86 | TRPC5 (0.79) | ALDH1A1TRPC5TIPARPKCNH2TRPC4 | |
| SCHEMBL20831484 | 0.86 | TRPC5 (0.75) | ALDH1A1TRPC5POLBTIPARPKCNH2 | |
| SCHEMBL20817957 | 0.84 | ALDH1A1 (0.66) | ALDH1A1TRPC5POLBTIPARPKCNH2 | |
| SCHEMBL20831898 | 0.84 | TRPC5 (0.58) | ALDH1A1TRPC5POLBTIPARPKCNH2 | |
| SCHEMBL20831901 | 0.84 | ALDH1A1 (0.52) | ALDH1A1DRD2DRD4DRD3TRPC5 | |
| SCHEMBL20832177 | 0.84 | ALDH1A1 (0.51) | ALDH1A1DRD2DRD4DRD3TRPC5 | |
| SCHEMBL25687087 | 0.83 | DRD2 (0.67) | ALDH1A1DRD2DRD4DRD3GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055966-A2 | PYRIDAZINONES AND METHODS OF USE THEREOF | GOLDFINCH BIO, INC. (US) | 2019-03-21 | — | — | WO | disclosed |