⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198326 | 0.83 | — | — | |
| SCHEMBL12961898 | 0.78 | LMNA (0.31) | — | |
| SCHEMBL18676244 | 0.75 | — | — | |
| SCHEMBL21899217 | 0.75 | L3MBTL1 (0.36) | — | |
| SCHEMBL11539161 | 0.72 | ELANE (0.38) | — | |
| SCHEMBL11537498 | 0.70 | — | — | |
| SCHEMBL890082 | 0.70 | — | — | |
| SCHEMBL22856238 | 0.69 | — | — | |
| SCHEMBL10197111 | 0.68 | — | — | |
| SCHEMBL668578 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-11691982-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2023-07-04 | — | — | US | disclosed |
| US-20200407369-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-12-31 | — | — | US | disclosed |
| US-20200216463-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
| US-10301319-B2 | Thailanstatin analogs | PH PHARMA CO., LTD. (KR) | 2019-05-28 | — | — | US | disclosed |
| US-20190084996-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2019-03-21 | — | — | US | disclosed |