Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.33 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363510 | 0.77 | TLR8 (0.44) | ELANETLR8TLR7KDM4ENPSR1 | |
| SCHEMBL11539177 | 0.73 | ELANE (0.38) | ELANETLR8TLR7KDM4ENPSR1 | |
| SCHEMBL11535323 | 0.72 | ELANE (0.43) | ELANETLR8 | |
| SCHEMBL20833367 | 0.72 | — | — | |
| SCHEMBL11539500 | 0.71 | DNM2 (0.44) | ELANETLR8NPSR1 | |
| SCHEMBL11539785 | 0.70 | TLR8 (0.51) | ELANETLR8KDM4ENPSR1L3MBTL1 | |
| SCHEMBL21700132 | 0.67 | ELANE (0.43) | ELANE | |
| SCHEMBL1527329 | 0.66 | ELANE (0.45) | ELANEKDM4E | |
| SCHEMBL11537211 | 0.66 | ELANE (0.39) | ELANETLR8KDM4ECYP1A2 | |
| SCHEMBL17995536 | 0.66 | ESR1 (0.53) | TLR8KDM4ESLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |