Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18973547 | 0.89 | BTN3A1 (0.46) | MEN1KMT2AALDH1A1BTN3A1 | |
| SCHEMBL20833582 | 0.87 | BTN3A1 (0.43) | ALDH1A1GAAMAPTBTN3A1HTT | |
| SCHEMBL22066302 | 0.87 | BTN3A1 (0.39) | ALDH1A1GAAMAPTBTN3A1HTT | |
| SCHEMBL22065046 | 0.87 | BTN3A1 (0.39) | ALDH1A1GAAMAPTBTN3A1HTT | |
| SCHEMBL22066300 | 0.87 | BTN3A1 (0.39) | KMT2AALDH1A1KDM4EGAAMAPT | |
| SCHEMBL22066301 | 0.82 | MRGPRX4 (0.43) | KMT2AALDH1A1MAPTBTN3A1HTT | |
| SCHEMBL20833545 | 0.81 | BTN3A1 (0.42) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL22066284 | 0.81 | BTN3A1 (0.42) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL22065060 | 0.81 | BTN3A1 (0.42) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL20587649 | 0.81 | BTN3A1 (0.42) | MEN1KMT2AALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | NuCana plc (GB) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181186-A1 | SYNTHESIS OF PHOSPHATE DERIVATIVES | PPA1, PPIP5K2, TYMP | MEN1 1081/4885KMT2A 3806/4885ALDH1A1 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.