SCHEMBL2083375

SCHEMBL2083375

CCN1CCC(Br)C1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11604283 0.88 INMT (0.38)
SCHEMBL7804696 0.84 L3MBTL1 (0.39)
SCHEMBL758907 0.78 ACE (0.42)
SCHEMBL14644332 0.78
SCHEMBL7506934 0.78 PIK3CD (0.65)
SCHEMBL8506955 0.78 PIK3CD (0.34)
SCHEMBL7510369 0.77 FPR2 (0.35)
SCHEMBL7619075 0.77 FPR2 (0.35)
SCHEMBL7619079 0.77 FPR2 (0.35)
SCHEMBL16691681 0.76 ACE (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8961946-B2 Hair processing agent and method for permanent waving hair SHOWA DENKO K.K. (JP) 2015-02-24 US disclosed
CN-101454282-B Process for producing heterocyclic mercapto compound SHOWA DENKO KK 2012-07-04 CN disclosed
EP-2024330-B1 PRODUCTION METHOD OF HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2012-04-25 EP disclosed
US-7902383-B2 Production method of heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-03-08 US disclosed
US-20090171095-A1 PRODUCTION METHOD OF HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO K.K. (JP) 2009-07-02 US disclosed
CN-101454282-A Process for producing heterocyclic mercapto compound SHOWA DENKO KK (JP) 2009-06-10 CN disclosed
EP-2024330-A1 PRODUCTION METHOD OF HETEROCYCLIC MERCAPTO COMPOUND Showa Denko K.K. (JP) 2009-02-18 EP disclosed
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; RESONAC CORPORATION (JP) 2008-04-10 US disclosed
WO-2007139215-A1 PRODUCTION METHOD OF HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO K.K. (JP) 2007-12-06 WO disclosed
EP-1827370-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR Showa Denko K.K. (JP) 2007-09-05 EP disclosed
WO-2006068276-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR SHOWA DENKO K.K. (JP) 2006-06-29 WO disclosed
US-20020045653-A1 C4 side-chain modified nodulisporic acid analogs SHIH THOMAS (US) 2002-04-18 US disclosed