Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.34 |
| ▸ | FURIN | P09958 | 5/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 4/20 | 0.31 |
| ▸ | NPY1R | P25929 | 3/20 | 0.31 |
| ▸ | NPY2R | P49146 | 3/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24349699 | 0.90 | SIRT5 (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL22139609 | 0.90 | SIRT5 (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL21788261 | 0.89 | FURIN (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL22692371 | 0.89 | FURIN (0.32) | FURINC3AR1LMNAPOLBKMT2A | |
| SCHEMBL20375788 | 0.85 | SIRT5 (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL18661755 | 0.85 | SIRT5 (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL25092038 | 0.85 | SIRT5 (0.44) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL21103418 | 0.85 | SIRT5 (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL17993275 | 0.85 | SIRT5 (0.44) | SIRT5FURINC3AR1SIRT6SIRT1 | |
| SCHEMBL16091799 | 0.85 | SIRT5 (0.36) | SIRT5FURINC3AR1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596270-B2 | Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates | SUTRO BIOPHARMA, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| US-20190083641-A1 | ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES | SUTRO BIOPHARMA, INC. | 2019-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596270-B2 | Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates | FOLR1, FOLR2, DHFR | SIRT5 3364/4885FURIN 2107/4885C3AR1 217/4885 |
| US-20190083641-A1 | ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES | FOLR1, FOLR2, DHFR | SIRT5 3364/4885FURIN 2107/4885C3AR1 217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.