⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3573509 | 0.67 | — | — | |
| SCHEMBL219971 | 0.67 | — | — | |
| SCHEMBL277660 | 0.67 | — | — | |
| SCHEMBL790366 | 0.63 | — | — | |
| SCHEMBL277285 | 0.62 | — | — | |
| SCHEMBL9685 | 0.61 | — | — | |
| SCHEMBL930479 | 0.61 | — | — | |
| SCHEMBL4924252 | 0.60 | CHRNB2 (0.36) | — | |
| SCHEMBL17103580 | 0.59 | — | — | |
| SCHEMBL1976412 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357218-A1 | N-FORMAMIDOPYRAZOLINE DERIVATIVE AS P2X3 RECEPTOR ANTAGONIST AND USE THEREOF | HANGZHOU WESTAN PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2023-11-09 | — | — | US | claimed |
| CN-113214240-B | N-formamido pyrazoline derivative as P2X3 receptor antagonist and application thereof | 杭州维坦医药科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| EP-4079725-A1 | N-CARBOXAMIDOPYRAZOLINE DERIVATIVE SERVING AS P2X3 RECEPTOR ANTAGONIST AND APPLICATIONS | Hangzhou Westan Pharmaceutical Technology Co., Ltd. (CN) | 2022-10-26 | — | — | EP | claimed |
| CN-113214240-A | N-formamido pyrazoline derivative as P2X3 receptor antagonist and application thereof | 杭州维坦医药科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| CN-111892585-A | N-formamido pyrazoline derivative as P2X3 receptor antagonist and application thereof | 杭州维坦医药科技有限公司 | 2020-11-06 | — | — | CN | claimed |
| EP-2036909-B1 | QUATERNARY AMMONIUM SALT COMPOUNDS OF SPIROCYCLOPIPERAZINES, PREPARATION METHODS AND USES THEREOF | UNIV BEIJING (CN) | 2016-05-04 | — | — | EP | claimed |
| EP-2271650-B1 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | claimed |
| EP-2493894-B1 | AZABICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2014-01-29 | — | — | EP | claimed |
| EP-2493893-B1 | AZABICYCLO[2.2.1]HEPTANE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2014-01-15 | — | — | EP | claimed |
| US-8309577-B2 | Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-13 | — | — | US | claimed |
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | claimed |
| US-6399608-B1 | FLUOXETINE, PAROXETINE OR SERTRALINE WITH 1,2,4-TRIAZOLO (4,3-B)PYRIDAZINE DERIVATIVE; NONSEDATING ANXIOLYTIC MODULATOR OF BENZODIAZEPINE BINDING SITE OF GAMMA AMINO-BUTYRIC ACID RECEPTOR; CENTRAL NERVOUS SYSTEM | MERCK SHARP & DOHME LTD. (GB) | 2002-06-04 | — | — | US | claimed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | claimed |
| US-5578595-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-11-26 | — | — | US | claimed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | claimed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | claimed |
| EP-0467840-A2 | Derivatives of cyclopropyl acetic acid | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | claimed |
| EP-0273300-A2 | Process for the one-bath single-stage dyeing of mixtures of carrier-free dyeable polyester fibres and cellulose fibres | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-06 | — | — | EP | claimed |
| EP-0007917-B1 | IMPROVEMENTS IN OR RELATING TO MEDIA FOR AFFINITY CHROMATOGRAPHY | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1984-02-01 | — | — | EP | claimed |
| US-4049661-A | FIBER-REACTIVE | CIBA-GEIGY AG (CH) | 1977-09-20 | — | — | US | claimed |