⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790366 | 0.69 | — | — | |
| SCHEMBL277285 | 0.67 | — | — | |
| SCHEMBL208381 | 0.67 | — | — | |
| SCHEMBL219971 | 0.67 | — | — | |
| SCHEMBL4723326 | 0.62 | TERT (0.31) | — | |
| SCHEMBL4919465 | 0.62 | — | — | |
| SCHEMBL53381 | 0.61 | — | — | |
| SCHEMBL8922905 | 0.61 | — | — | |
| SCHEMBL947 | 0.56 | — | — | |
| SCHEMBL13716342 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024141444-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | claimed |
| EP-3634975-B1 | 17-OXIMES OF 15.BETA.-[3-PROPANAMIDO]-SUBSTITUTED ESTRA-1,3,5(10)-TRIEN-17-ONES FOR USE IN INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASES | ORGANON R&D FINLAND LTD (FI) | 2024-02-28 | — | — | EP | claimed |
| CN-110945007-B | 15 beta- [ 3-propionylamino ] -substituted estra-1, 3,5 (10) -trien-17-one compounds and 17-oximes thereof for inhibiting 17 beta-hydroxysteroid dehydrogenases | 佛恩多制药有限公司 | 2022-11-18 | — | — | CN | claimed |
| US-20220127303-A1 | THERAPEUTICALLY ACTIVE STEROIDAL DERIVATIVES | FORENDO PHARMA LTD (FI) | 2022-04-28 | — | — | US | claimed |
| US-11254703-B2 | Therapeutically active steroidal derivatives | FORENDO PHARMA LTD (FI) | 2022-02-22 | — | — | US | claimed |
| CN-108137547-B | Heterocyclic compounds useful as TNF alpha modulators | 百时美施贵宝公司 | 2021-11-12 | — | — | CN | claimed |
| EP-3807266-A1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2021-04-21 | — | — | EP | claimed |
| CN-112585128-A | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-110746479-B | Compound and preparation method and application thereof | 山东师范大学 | 2021-01-08 | — | — | CN | claimed |
| US-10865191-B2 | Heterocyclic compounds useful as modulators of TNF alpha | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-12-15 | — | — | US | claimed |
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | claimed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | claimed |
| US-RE34722-E | Antiulcer agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | claimed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | claimed |
| US-5175161-A | Treatment of glaucoma | SANKYO COMPANY, LIMITED (JP) | 1992-12-29 | — | — | US | claimed |
| EP-0391721-A2 | Ocular hypotensive agents | Sankyo Company Limited (JP) | 1990-10-10 | — | — | EP | claimed |
| US-4800201-A | 1,4-thiazine derivative, and cardiotonic agent comprising it as effective component | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-01-24 | — | — | US | claimed |
| EP-0233287-A1 | 1,4-THIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND CARDIOTONICS CONTAINING THE SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1987-08-26 | — | — | EP | claimed |
| US-4578381-A | ANTIULCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-25 | — | — | US | claimed |