⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277660 | 0.67 | — | — | |
| SCHEMBL208381 | 0.67 | — | — | |
| SCHEMBL3573509 | 0.67 | — | — | |
| SCHEMBL790366 | 0.63 | — | — | |
| SCHEMBL277285 | 0.62 | — | — | |
| SCHEMBL4924252 | 0.60 | CHRNB2 (0.36) | — | |
| SCHEMBL17103628 | 0.59 | — | — | |
| SCHEMBL17103580 | 0.59 | — | — | |
| SCHEMBL1397445 | 0.56 | — | — | |
| SCHEMBL164220 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745995-A | ATR inhibitors and uses thereof | 苏州浦合医药科技有限公司 | 2023-03-07 | — | — | CN | claimed |
| US-8242116-B2 | Fused thiazole derivatives as kinase inhibitors | UCB PHARMA S.A. (BE) | 2012-08-14 | — | — | US | claimed |
| EP-2035436-B1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2011-05-25 | — | — | EP | claimed |
| US-20100137302-A1 | Fused Thiazole Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-06-03 | — | — | US | claimed |
| WO-2009122148-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-08 | — | — | WO | claimed |
| WO-2009071888-A1 | PYRROLOTHIAZOLES AS PI3-KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | claimed |
| WO-2009071890-A1 | TRICYCLIC KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | claimed |
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | claimed |
| EP-2035436-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-18 | — | — | EP | claimed |
| WO-2008001076-A1 | FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2008-01-03 | — | — | WO | claimed |
| US-7060110-B2 | Dyeing composition for dyeing keratinous fibres comprising a particular dicationic monoazo dye | L'OREAL (FR) | 2006-06-13 | — | — | US | claimed |
| EP-1268469-B1 | N-(HETEROCYCLYL)BENZENE OR PYRIDINE SULPHONAMIDES AS ANTITHROMBOTIC AGENTS AND ANTICOAGULANTS | SANOFI SYNTHELABO (FR) | 2004-06-16 | — | — | EP | claimed |
| US-20040093676-A1 | Novel dyeing composition for dyeing keratinous fibres comprising a particular dicationic monoazo dye | L'OREAL S.A. (FR) | 2004-05-20 | — | — | US | claimed |
| US-20040058970-A1 | Cognition enhancing derivatives of isoxazole triazoloindane GABA-A alpha 5 receptor subunit ligands | MERCK SHARP & DOHME LTD. (GB) | 2004-03-25 | — | — | US | claimed |
| US-6680329-B2 | N-(heterocyclyl)benzene or pyridinesulphonamides as antithrombotic agents and anticoagulants | SANOFI-SYNTHELABO (FR) | 2004-01-20 | — | — | US | claimed |
| US-20030207920-A1 | N-(heterocyclyl)benzene or pyridinesulphonamides as antithrombotic agents and anticoagulants | SANOFI-AVENTIS (FR) | 2003-11-06 | — | — | US | claimed |
| CN-115745995-A | ATR inhibitors and uses thereof | 苏州浦合医药科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-3752491-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Nuvation Bio Inc. (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-0368160-A1 | Tetralin derivatives | MERCK PATENT GmbH (DE) | 1990-05-16 | — | — | EP | disclosed |
| EP-0363883-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1990-04-18 | — | — | EP | disclosed |