Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 6/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20838483 | 0.82 | MAPT (0.56) | MAPTKDM4EHTTPKMGAA | |
| SCHEMBL3819661 | 0.75 | MAPT (0.58) | CCR1MAPTKDM4EHTTGAA | |
| SCHEMBL18497871 | 0.72 | KDM4E (0.44) | CCR1MAPTKDM4EHTTPKM | |
| SCHEMBL20908523 | 0.71 | KDM4E (0.44) | CCR1MAPTKDM4EHTTPKM | |
| SCHEMBL18497873 | 0.71 | KDM4E (0.46) | CCR1MAPTKDM4EHTTPKM | |
| SCHEMBL29912575 | 0.69 | KDM4E (0.42) | CCR1MAPTKDM4EHTTPKM | |
| SCHEMBL18515970 | 0.69 | KDM4E (0.42) | CCR1MAPTKDM4EHTTPKM | |
| SCHEMBL11505225 | 0.67 | GAA (0.39) | GAAHSD17B10 | |
| SCHEMBL20838470 | 0.66 | CCR1 (0.33) | CCR1TERT | |
| SCHEMBL4738382 | 0.63 | SLC40A1 (0.62) | MAPTHTTGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3466931-B1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | UNIV GUANGDONG TECHNOLOGY (CN) | 2024-01-10 | — | — | EP | disclosed |
| US-10807957-B2 | Tetradentate chelating monoquinoline derivative, manufacturing method thereof, and application of same as metal ion regulator for neurodegenerative disease | UNIV GUANGDONG TECHNOLOGY (CN) | 2020-10-20 | — | — | US | disclosed |
| US-10807957-B2 | Tetradentate chelating monoquinoline derivative, manufacturing method thereof, and application of same as metal ion regulator for neurodegenerative disease | UNIV GUANGDONG TECHNOLOGY (CN) | 2020-10-20 | — | — | US | disclosed |
| EP-3466931-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | Guangdong University Of Technology (CN) | 2019-04-10 | — | — | EP | disclosed |
| US-20190092730-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | GUANGDONG UNIVERSITY OF TECHNOLOGY | 2019-03-28 | — | — | US | disclosed |
| US-20190092730-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | GUANGDONG UNIVERSITY OF TECHNOLOGY | 2019-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807957-B2 | Tetradentate chelating monoquinoline derivative, manufacturing method thereof, and application of same as metal ion regulator for neurodegenerative disease | SOD1, SLC30A6, SLC30A7 | CCR1 4551/4885MAPT 31/4885KDM4E 2023/4885 |
| US-20190092730-A1 | TETRADENTATE CHELATING MONOQUINOLINE DERIVATIVE, MANUFACTURING METHOD THEREOF, AND APPLICATION OF SAME AS METAL ION REGULATOR FOR NEURODEGENERATIVE DISEASE | SOD1, SLC30A6, SLC30A7 | CCR1 4551/4885MAPT 31/4885KDM4E 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.