Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177166 | 0.85 | BRD4 (0.47) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL21843252 | 0.82 | BRD4 (0.56) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL23611731 | 0.77 | BRD4 (0.49) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL26081236 | 0.77 | BRD4 (0.51) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL750492 | 0.77 | BRD4 (0.51) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL5011954 | 0.76 | TSHR (0.54) | MAPTBRD4L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14398367 | 0.75 | KDM4E (0.60) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL159285 | 0.75 | BRD4 (0.50) | MAPTBRD4KDM4EALOX15L3MBTL1 | |
| SCHEMBL24335090 | 0.75 | HTT (0.46) | MAPTKDM4EALOX15CYP1A2ALDH1A1 | |
| SCHEMBL13697273 | 0.74 | PDE3B (0.35) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684184-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| EP-3684184-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| EP-3684765-B1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-11-30 | — | — | EP | disclosed |
| CN-111372456-B | Herbicidally active pyridyl-/pyrimidinyl-pyrazine derivatives | 先正达参股股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-11434221-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-09-06 | — | — | US | disclosed |
| US-11434221-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-09-06 | — | — | US | disclosed |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3684765-A1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| EP-3684184-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| CN-111372456-A | Herbicidally active pyridyl-/pyrimidinyl-pyrazine derivatives | 先正达参股股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111315731-A | Pyrazine-4-carbamate or-urea derivatives as herbicides | 先正达参股股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| WO-2019057723-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057725-A1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057725-A1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057723-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434221-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | DDT, PLPBP, CPS1 | MAPT 1668/4885BRD4 832/4885KDM4E 418/4885 |
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | DDT, HPD, PLPBP | MAPT 3772/4885BRD4 1621/4885KDM4E 1224/4885 |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | DDT, HPD, PLPBP | MAPT 3772/4885BRD4 1621/4885KDM4E 1224/4885 |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | DDT, HPD, PLPBP | MAPT 3772/4885BRD4 1621/4885KDM4E 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.