Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885204 | 0.88 | MAPKAPK2 (0.41) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL19918407 | 0.85 | MAPKAPK2 (0.40) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL9897763 | 0.85 | ATR (0.39) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL26797587 | 0.85 | MAPKAPK2 (0.39) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL2885806 | 0.84 | MAPKAPK2 (0.41) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL26969974 | 0.84 | MAPKAPK2 (0.39) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL30708749 | 0.84 | MAPKAPK2 (0.39) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL7462692 | 0.83 | ATR (0.42) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL29537838 | 0.82 | ATR (0.44) | LCKMAPKAPK2ATRSTK17BSTK17A | |
| SCHEMBL6383116 | 0.82 | SYK (0.39) | LCKMAPKAPK2ATRSTK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684184-B1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-21 | — | — | EP | disclosed |
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-20 | — | — | US | disclosed |
| EP-3684765-B1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-11-30 | — | — | EP | disclosed |
| CN-111372456-B | Herbicidally active pyridyl-/pyrimidinyl-pyrazine derivatives | 先正达参股股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| US-11434221-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-09-06 | — | — | US | disclosed |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-12 | — | — | US | disclosed |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-25 | — | — | US | disclosed |
| EP-3684764-B1 | PYRAZINE-4-CARBAMATE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-10 | — | — | EP | disclosed |
| US-20200308137-A1 | Pyrazine-4-Carbamate or -Urea Derivatives As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-10-01 | — | — | US | disclosed |
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
| EP-3684184-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| EP-3684764-A1 | PYRAZINE-4CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| EP-3684765-A1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | Syngenta Participations AG (CH) | 2020-07-29 | — | — | EP | disclosed |
| CN-111372456-A | Herbicidally active pyridyl-/pyrimidinyl-pyrazine derivatives | 先正达参股股份有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-111315731-A | Pyrazine-4-carbamate or-urea derivatives as herbicides | 先正达参股股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111315732-A | Pyrazine-4-carbamate or-urea derivatives as herbicides | 先正达参股股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| WO-2019057724-A1 | PYRAZINE-4CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057725-A1 | PYRAZINE-4-CARBAMATE OR -UREA DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019057723-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11434221-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | DDT, PLPBP, CPS1 | LCK 3030/4885MAPKAPK2 2681/4885EDNRA 4735/4885 |
| US-20200308137-A1 | Pyrazine-4-Carbamate or -Urea Derivatives As Herbicides | DDT, PLPBP, CPS1 | LCK 3034/4885MAPKAPK2 2750/4885EDNRA 4733/4885 |
| US-20200267984-A1 | Herbicidally Active Pyridyl-/Pyrimidyl-Pyrazine Derivatives | DDT, HPD, PLPBP | LCK 2543/4885MAPKAPK2 2008/4885EDNRA 4704/4885 |
| US-11678665-B2 | Pyrazine-4-carbamate or -urea derivatives as herbicides | DDT, PLPBP, CPS1 | LCK 3034/4885MAPKAPK2 2750/4885EDNRA 4733/4885 |
| US-20220144801-A1 | HERBICIDALLY ACTIVE PYRIDYL-/PYRIMIDYL-PYRAZINE DERIVATIVES | DDT, HPD, PLPBP | LCK 2543/4885MAPKAPK2 2008/4885EDNRA 4704/4885 |
| US-11229205-B2 | Herbicidally active pyridyl-/pyrimidyl-pyrazine derivatives | DDT, HPD, PLPBP | LCK 2543/4885MAPKAPK2 2008/4885EDNRA 4704/4885 |
| US-20200267983-A1 | Pyrazine-4Carbamate or -Urea Derivatives As Herbicides | PLPBP, PDXK, HPD | LCK 3175/4885MAPKAPK2 2595/4885EDNRA 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.