Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.57 |
| ▸ | PPARD | Q03181 | 10/20 | 0.57 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.44 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839752 | 0.88 | NR1H4 (0.73) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20839777 | 0.86 | NR1H4 (0.56) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20839618 | 0.84 | NR1H4 (0.53) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20839957 | 0.83 | NR1H4 (0.58) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20839668 | 0.83 | NR1H4 (0.56) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20839629 | 0.82 | NR1H4 (0.56) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20839724 | 0.78 | CYP3A4 (0.52) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20840671 | 0.78 | NR1H4 (0.54) | NR1H4PPARDPPARGPPARAABCG2 | |
| SCHEMBL20852079 | 0.74 | NR1H4 (0.81) | NR1H4PPARDPPARGPPARARXFP1 | |
| SCHEMBL20839943 | 0.73 | FADS1 (0.52) | NR1H4PPARGPPARAABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |