Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6755590 | 0.84 | NOTUM (0.43) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL7921949 | 0.81 | KMT2A (0.43) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL20839726 | 0.81 | KMT2A (0.46) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL7932429 | 0.81 | KMT2A (0.46) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL31191940 | 0.81 | KMT2A (0.43) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL4747081 | 0.77 | PTGS2 (0.47) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL459445 | 0.77 | KMT2A (0.43) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL31191995 | 0.77 | KMT2A (0.40) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL981963 | 0.77 | KMT2A (0.70) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL3277352 | 0.74 | ALDH1A1 (0.39) | KMT2AMAPTMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |