Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192001 | 0.81 | NOTUM (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL20839623 | 0.81 | NR1H4 (0.41) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5763911 | 0.77 | NR1H4 (0.62) | MAPTKDM4EKMT2ANPC1RAB9A | |
| SCHEMBL31538740 | 0.77 | NR1H4 (0.37) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL19732314 | 0.75 | TSHR (0.40) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20839735 | 0.74 | KMT2A (0.43) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL16397645 | 0.73 | ALOX5 (0.64) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL212724 | 0.73 | ALOX5 (0.64) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL23532714 | 0.71 | ALOX5 (0.62) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5770308 | 0.71 | ALOX5 (0.62) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074109-B2 | Fluorine-containing polymer, the preparation process and use thereof, pigment dispersion and the preparation process | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2015-07-07 | — | — | US | disclosed |
| US-20140142220-A1 | FLUORINE-CONTAINING POLYMER, THE PREPARATION PROCESS AND USE THEREOF, PIGMENT DISPERSION AND THE PREPARATION PROCESS | BOE TECHNOLOGY GROUP CO., LTD. (CN) | 2014-05-22 | — | — | US | disclosed |
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-04-08 | — | — | US | disclosed |
| EP-2121569-A2 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008074755-A2 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087496-A1 | NOVEL CINNAMIC AMIDE DERIVATIVES USEFUL AS ION CHANNEL MODULATORS | TRPV1, TRPA1, TRPM8 | ALDH1A1 1865/4885MAPT 1755/4885KDM4E 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.