Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 5/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839715 | 0.87 | NR1H4 (0.61) | NR1H4PPARGPPARAPPARDABCG2 | |
| SCHEMBL20839943 | 0.78 | FADS1 (0.52) | NR1H4PPARGPPARAABCG2SIRT2 | |
| SCHEMBL7457415 | 0.76 | SIRT2 (0.53) | NR1H4PPARGPPARAPPARDABCG2 | |
| SCHEMBL20839724 | 0.75 | CYP3A4 (0.52) | NR1H4PPARGPPARAPPARDABCG2 | |
| SCHEMBL20839629 | 0.75 | NR1H4 (0.56) | NR1H4PPARGPPARAPPARDABCG2 | |
| SCHEMBL20839494 | 0.75 | NR1H4 (0.45) | NR1H4PPARGPPARAPPARDRXFP1 | |
| SCHEMBL20839484 | 0.75 | ABCG2 (0.68) | ABCG2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20839668 | 0.74 | NR1H4 (0.56) | NR1H4PPARGPPARAPPARDRXFP1 | |
| SCHEMBL15591247 | 0.72 | PTGER4 (0.49) | NR1H4MEN1KMT2ABRD4MAPT | |
| SCHEMBL20852275 | 0.72 | NR1H4 (0.71) | NR1H4PPARGPPARAPPARDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019057969-A1 | DUAL AGONISTS OF FXR AND PPARδ AND THEIR USES | Johann Wolfgang Goethe-Universität (DE) | 2019-03-28 | — | — | WO | disclosed |