Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444190 | 0.80 | LMNA (0.40) | TDP1L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL28433238 | 0.78 | CYP19A1 (0.58) | SMN1; SMN2HSD17B10TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL28435572 | 0.77 | KMT2A (0.44) | TSHRHSD17B10TDP1ALDH1A1KDM4E | |
| SCHEMBL28438221 | 0.77 | ALDH1A1 (0.37) | TDP1L3MBTL1ALDH1A1KDM4ELMNA | |
| SCHEMBL28441990 | 0.77 | ALDH1A1 (0.46) | TDP1L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL28433232 | 0.77 | HTT (0.42) | TSHRSMN1; SMN2HSD17B10L3MBTL1ALDH1A1 | |
| SCHEMBL28438215 | 0.76 | POLB (0.43) | TSHRSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL28438115 | 0.76 | MEN1 (0.44) | SMN1; SMN2TDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL28438180 | 0.76 | CNR2 (0.41) | SMN1; SMN2L3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL28440223 | 0.74 | PIM1 (0.48) | SMN1; SMN2HSD17B10TDP1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3684767-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2020-07-29 | — | — | EP | disclosed |
| WO-2019058393-A1 | HETEROCYCLIC COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-03-28 | — | — | WO | disclosed |