Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | RORA | P35398 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444190 | 0.86 | LMNA (0.40) | FABP4FABP5ALDH1A1LMNANPC1 | |
| SCHEMBL28433235 | 0.84 | CNR2 (0.40) | CNR2FABP4FABP5ALDH1A1LMNA | |
| SCHEMBL28438221 | 0.83 | ALDH1A1 (0.37) | FABP4FABP5ALDH1A1LMNANPC1 | |
| SCHEMBL28440223 | 0.83 | PIM1 (0.48) | CNR2FABP4FABP5LMNASMN1; SMN2 | |
| SCHEMBL28433238 | 0.78 | CYP19A1 (0.58) | ALDH1A1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL28435572 | 0.77 | KMT2A (0.44) | ALDH1A1LMNANPC1MAPTHTT | |
| SCHEMBL2700703 | 0.76 | FABP4 (0.56) | CNR2FABP4FABP5HDAC1HDAC6 | |
| SCHEMBL541993 | 0.76 | FABP4 (0.56) | CNR2FABP4FABP5HDAC1HDAC6 | |
| SCHEMBL20840111 | 0.76 | TSHR (0.46) | ALDH1A1LMNANPC1MAPTHTT | |
| SCHEMBL28438115 | 0.76 | MEN1 (0.44) | ALDH1A1LMNANPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928121-B | High-efficiency preparation method of 3-substituted-benzo five-membered heterocycle-2-carbonyl compound | 暨南大学 | 2020-05-12 | — | — | CN | disclosed |