SCHEMBL20840686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1766795	0.90	P2RX1 (0.47)	P2RX1KMT2AKCNMA1MEN1CYP2C9
	SCHEMBL29695914	0.85	P2RX1 (0.46)	P2RX1KMT2AKCNMA1MEN1CYP2C9
	SCHEMBL22497571	0.85	P2RX1 (0.43)	P2RX1KMT2AKCNMA1MEN1CYP2C9
	SCHEMBL1766569	0.85	P2RX1 (0.46)	P2RX1KMT2AKCNMA1MEN1CYP2C9
	SCHEMBL29549704	0.85	P2RX1 (0.46)	P2RX1KMT2AKCNMA1MEN1CYP2C9
	SCHEMBL29550296	0.85	PTGS1 (0.38)	P2RX1
	SCHEMBL28395430	0.85	PTGS1 (0.38)	P2RX1
	SCHEMBL20839522	0.83	RXFP1 (0.37)	—
	SCHEMBL20839536	0.83	P2RX1 (0.41)	P2RX1KMT2AKCNMA1MEN1CYP2C9
	SCHEMBL20839525	0.81	HTR1F (0.42)	KMT2AMEN1LMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.